![]() ![]() “What is even more compelling about these data is the substantial protective effect of vaccines with respect to adverse events such as acute kidney injury, intracranial hemorrhage, and anemia, probably because infection was prevented,” writes Grace Lee, a professor of medicine at Stanford who penned an editorial commentary on the study. The Moderna vaccine is very similar to Pfizer’s, so it’s likely the results would be similar if the same study could be done with that vaccine - but without the numbers, we don’t know for sure. The vaccine involved was the Pfizer one, so this analysis may not apply to other vaccines like the AstraZeneca. ![]() Take-home message: Low excess risk of adverse events after vaccination, higher after infection. Vaccine safety: We compared excess adverse events after #COVID19 vaccination (Pfizer-BioNTech) and after documented #SARSCoV2 infection. (Each person was matched to a control of the same age, sex, home location, and health status.) The study was conducted as a medical records analysis in Israel, and it compared 884,828 vaccinated people with an equal number of unvaccinated controls, and 173,106 people with a COVID infection and an equal number of controls. People who got the vaccine were at substantially higher risk for lymphadenopathy (swollen lymph nodes).People who got COVID were at substantially higher risk for arrhythmia (irregular heartbeat), myocardial infarction (heart attack), deep-vein thrombosis (blood clots in places like the legs), pulmonary embolism (blood clots in the lungs), myocarditis (inflammation of the heart muscle), pericarditis (inflammation of tissues near the heart), intracerebral hemorrhage (bleeding in the brain), and thrombocytopenia (low platelet counts).(Mild reactions like fever and soreness at the injection site weren’t included.) Here’s what they found: A new study in the New England Journal of Medicine set out to answer this question, comparing the moderate to serious symptoms people experience after the Pfizer vaccine with those that people experience with a COVID infection. ![]()
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